IL-13 Human Matched Antibody Pair/人IL-13匹配抗体对
货号：BMS231-3MST
规格：10 x 96 tests
价格：6614
产品类型：标准品和抗体对
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 1.6 pg/mL |
| 检测范围 | 1.6-100 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 2 hr 10 min |
测试时间 | 24 hr |
Homogenous (no wash) | No |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 10 x 96 tests |
组份 | - 捕获（包被）抗体 - 检测抗体 - 标准品 -SAV-HRP |
储存温度 | -20°C |
| Protein name | IL-13 |
| Protein aliases | IL-13, Interleukin-13 |
物种（Tested） | 人 |
试剂盒类型 | 匹配抗体对 |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | IL-13, IL13, NC30, P600 |
| Gene ID | (Human) 3596 |
| Gene symbol | IL13 |
| UniProt ID | (Human) P35225 |
The Human IL-13 Matched Antibody Pair Kit comes with pre-matched antibody pairs, standards, and streptavidin-HRP to develop your own enzyme linked immunosorbent assays (ELISA) to detect and quantify protein levels of human IL-13. Buffer reagents and microplates needed to complete the ELISA reaction are sold separately.Principle of the methodELISAs are designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody is coated to the bottom of the wells of a microplate, which is an overnight process. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. A sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.Target informationIL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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