ScienCell GK025 人类Notch信号通路qPCR检测试剂盒,uman Notch Signaling Pathway qPCR Array Kit

ScienCell 研究实验室（ScienCell）是一家生物技术公司，其使命是实验和治疗用细胞和细胞相关产品的研究和发展。 ScienCell为研究界提供各种高质量的正常的人类和动物细胞，细胞培养基和试剂，培养基添加因子，细胞来源的RNA，cDNA和蛋白质。ScienCell的科学家们以改善生活质量，实现细胞的能力，打击人类退化性疾病为目的研究和开发各种细胞治疗策略。ScienCell总部设在美国加利福尼亚州圣地亚哥，公司成立于1999年。

北京作为ScienCell品牌的代理商，为客户提供，正规进口，保证原装正品，货期稳定，折扣好的服务标准。

GK025 ScienCell人类Notch信号通路qPCR检测试剂盒，uman Notch Signaling Pathway qPCR Array Kit，产品简介：

产品品牌: ScienCell

产品货号：GK025

产品名称：GK025 ScienCell人类Notch信号通路qPCR检测试剂盒，uman Notch Signaling Pathway qPCR Array Kit

产品规格：One 96-well plate, one 20ul reaction per well

GK025 ScienCell人类Notch信号通路qPCR检测试剂盒，uman Notch Signaling Pathway qPCR Array Kit， 产品说明：

ScienCell 的 GeneQuery™ Human Notch 信号通路 qPCR 芯片试剂盒 （GQH-NCH） 旨在促进参与人类 Notch 分子通路的 88 个关键基因的基因表达谱分析，重点是 Notch1 信号转导。 如何根据其作用对所包含的基因进行分组的简要示例如下所示：

规范配体：JAG1、JAG2、DLL1、DLL3DLL4

非规范配体：WNT1，DNER，CNTN1，NOV，SHH

受体：缺口1，缺口2，缺口3，缺口4

转录抑制因子：HEY1、HEY2、ESR1、HES1、HES7

蛋白水解：ADAM17、PSEN1、FURIN、POFUT1、PSENEN

GeneQuery™ qPCR 芯片试剂盒采用 96 孔板格式的 qPCR 就绪，每个孔包含一个引物组，可识别并有效扩增特定靶基因的 cDNA。精心设计的引物确保：（i）qPCR分析中的最佳退火温度为65°C（含2 mM Mg2+且不含DMSO）;（ii）除非另有说明，否则引物集可识别靶基因的所有已知转录本变体;（iii）只有一个基因被扩增。每个引物组都已通过qPCR和熔解曲线分析和凝胶电泳进行了验证。

ScienCell's GeneQuery™ Human Notch Signaling Pathway qPCR array kit (GQH-NCH) is designed to facilitate gene expression profiling of 88 key genes involved in the human Notch molecular pathway with an emphasis on Notch1 signal transduction. Brief examples of how included genes may be grouped according to their roles are shown below:

· Canonical ligands: JAG1, JAG2, DLL1, DLL3DLL4

· Noncanonical ligands: WNT1, DNER, CNTN1, NOV, SHH

· Receptors: NOTCH1, NOTCH2, NOTCH3, NOTCH4

· Transcriptional repressors: HEY1, HEY2, ESR1, HES1, HES7

· Proteolysis: ADAM17, PSEN1, FURIN, POFUT1, PSENEN

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis.

GeneQuery™ 人类缺口信号通路 qPCR 阵列板布局*（8 个粗体和斜体对照）

提示：基因选择可能会根据新的研究和开发进行更新

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