BIO-RAD MCA4738 Mouse anti Clostridium difficile Toxin B,Mouse anti Clostridium difficile Toxin B

2024-10-22

Mouse anti Clostridium difficile Toxin B

货号:MCA4738

规格:0.1mg

价格:4361

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Clostridium difficile Toxin B

物种:其它

宿主:小鼠

抗体亚型:IgG1, kappa

荧光染料:Alexa Fluor 488

产品介绍
Mouse anti Clostridium difficile Toxin B antibody, clone 5158recognizesClostridium difficiletoxin B. No reaction is observed with toxin A.Clostridium difficileis a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics.Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modify the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
产品详情
Target SpeciesBacterial
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.1% Sodium Azide (NaN3)
Approx. Protein ConcentrationsIgG concentration 0.1mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/20
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Voth, D.E. & Ballard, J.D. (2005) Clostridium difficile toxins: mechanism of action and role in disease.Clin Microbiol Rev. 18 (2): 247-63.

技术参数

产品应用 Flow

产品类型 单克隆抗体

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