BIO-RAD MCA4703PE Rat anti Mouse CD44:RPE,Rat anti Mouse CD44:RPE-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA4703PE Rat anti Mouse CD44:RPE,Rat anti Mouse CD44:RPE

2024-10-22

Rat anti Mouse CD44:RPE

货号：MCA4703PE

规格：0.1 mg

价格：3162

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD44

物种：小鼠

宿主：大鼠

抗体亚型：IgG1, kappa

荧光染料：PE

产品介绍
Rat anti Mouse CD44 antibody, clone IM7recognizes CD44, also known as H-CAM, HUTCH and lymphocyte antigen 24 (Ly-24).CD44 is a cell surface receptor for hyaluronic acid, although it can also interact with other ligands such as collagens and matrix metalloproteinases. This protein plays a role in a variety of cellular functions, such as adhesion, lymphocyte activation and lymph node homing. It is also involved in cell migration and plays a role in tumor metastasis. CD44 has many distinct isoforms responsible for its functional diversity.Rat anti Mouse CD44 antibody, clone IM7 recognizes all isoforms of CD44 and has been reported to inhibit a delayed-type hypersensitivity responsein vivoand to induce complement-mediated cytotoxicity.
产品详情
Target Species	Mouse
Product Form	Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Preparation	Purified IgG prepared by affinity chromatography
Buffer Solution	Phosphate buffered saline
Immunogen	Dexamethasone-induced myeloid leukemia M1 cells.
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Approx. Protein Concentrations	IgG concentration 0.2 mg/ml
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
RPE 488nm laser	496	578
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/5
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
文献
1.Mckallip, R.J.et al.(2002) Role of CD44 in activation-induced cell death: CD44-deficient mice exhibit enhanced T cell response to conventional and superantigens.Int Immunol. 14 (9): 1015-26.2.Camp, R.L.et al.(1993) CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation.J Exp Med. 178: 497-507.3.Brocke, S.et al.(1999) Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment.Proc Natl Acad Sci U S A. 96: 6896-901.4.Lesley, J.et al.(1992) Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody.J Exp Med. 175: 257-66.

技术参数

产品应用 Flow

产品类型单克隆抗体

推荐用于 Flow

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BIO-RAD MCA4703PE Rat anti Mouse CD44:RPE,Rat anti Mouse CD44:RPE

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