Bio-Rad mouse anti SOS1 MCA2887,mouse anti SOS1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad mouse anti SOS1 MCA2887,mouse anti SOS1

2024-10-22

mouse anti SOS1

货号：MCA2887

规格：0.1 mg

价格：2550

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：SOS1

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：SOS-01

荧光染料：Purified

产品介绍
Mouse anti Human SOS1 antibody, clone SOS-01recognizes SOS1 (son of sevenless homolog 1), a ubiquitously expressed 1333 amino acid ~150 kDa intracellular protein and bifunctional guanine nucleotide exchange factor (GEF), which plays a role in growth and differentiation signalling pathways and in actin reorganization, by acting as a regulator of Ras and Rac/Rho GTPases.Mutations in the SOS1 gene are responsible for the rare oral overgrowth condition known as gingival fibromatosis 1 (Hartet al.2002), and also the cause of the relatively common autosomal dominant disorder Noonan syndrome type 4 (NS4), characterized by short stature, congenital heart malformation, bleeding diathesis and distinctive facial features (Hannaet al.2009).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution	Phosphate buffered saline
Immunogen	Synthetic peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human SOS1.
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Approx. Protein Concentrations	IgG concentration 1 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	0.5	1.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Scita, G.et al.(2000) Signaling from Ras to Rac and beyond: not just a matter of GEFs.EMBO J. 19 (11): 2393-8.

技术参数

产品应用 ELISA;WB;IF

产品类型单克隆抗体

推荐用于 ELISA;WB;IF

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Bio-Rad mouse anti SOS1 MCA2887,mouse anti SOS1

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