Bio-Rad mouse anti CLOSTRIDIUM DIFFICILE TOXIN A,mouse anti CLOSTRIDIUM DIFFICILE TOXIN A

2024-10-22

mouse anti CLOSTRIDIUM DIFFICILE TOXIN A

货号:MCA2597

规格:0.1 mg

价格:5950

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Clostridium difficile Toxin A

物种:Bacterial

宿主:小鼠

抗体亚型:IgG1

克隆号:5155

荧光染料:Purified

产品介绍
Mouse antiClostridium dificiletoxin A antibody, clone 5155recognizesClostridium difficiletoxin A. No reaction is observed withClostridium difficiletoxin B, tetanus toxoid,Pseudomonas aeruginosaandYersinia enterocoliticaClostridium difficileis a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics.Toxin A (TcdA) is a large exotoxin which is an essential virulence factor forC. difficileinfection. TcdA has a molecular mass of ~308 kDa and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
产品详情
Target SpeciesBacterial
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Approx. Protein ConcentrationsIgG concentration 0.1mg/ml
Fusion PartnersCells from immunised mice were fused with cells of the mouse Sp-2/0-Ag14 myeloma cell line.
ImmunogenClostridium difficiletoxin A.
Preservative Stabilisers0.1%Sodium Azide (NaN3)
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
文献
1.Voth, D.E. & Ballard, J.D. (2005)Clostridium difficiletoxins: mechanism of action and role in disease.Clin Microbiol Rev. 18 (2): 247-63.

技术参数

产品应用 ELISA

产品类型 单克隆抗体

推荐用于 ELISA

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