Bio-Rad CD88抗体 MCA2456A647,Rat anti mouse CD88:Alexa Fluor647-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad CD88抗体 MCA2456A647,Rat anti mouse CD88:Alexa Fluor647

2024-10-22

Rat anti mouse CD88:Alexa Fluor647

货号：MCA2456A647,MCA2456A647T

规格：100 Tests/1ml,25 Tests/0.25ml

价格：3290,1216

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD88

物种：小鼠

宿主：大鼠

抗体亚型：IgG2a

克隆号：10/92

荧光染料：Alexa Fluor 647

产品介绍
Rat anti Mouse CD88 antibody, clone 10/92recognizes murine CD88, a 45 kDa G-protein coupled cell surface receptor, otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, a potent proinflammatory molecule and chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.Rat anti Mouse CD88 antibody, clone 10/92 does not block the binding of the C5a to murine CD88 (Souriet al.2003).
产品详情
Target Species	Mouse
Product Form	Purified IgG conjugated to Alexa Fluor® 647 - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Fusion Partners	Cells from immunised Lou/c rats were fused with cells of the X63-Ag8.653 myeloma cell line.
Acknowledgements	This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Buffer Solution	Phosphate buffered saline
Immunogen	RBL-2H3 transfected cells expressing murine C5aR.
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Preservative Stabilisers	0.09%Sodium Azide1%Bovine Serum Albumin
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
Alexa Fluor®647	650	665
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Soruri, A.et al. (2003) Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody.Immunol Lett. 88:47-52.2.Shagdarsuren, E.et al.(2010) C5a Receptor Targeting in Neointima Formation After Arterial Injury in Atherosclerosis-Prone Mice.Circulation. 122: 1026-36.3.Manthey, H.D.et al.(2011) Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice.FASEB J. 25: 2447-55.4.Cudaback, E.et al.(2011) Apolipoprotein E isoform-dependent microglia migration.FASEB J. 25: 2082-91.5.Ager, R.R.et al.(2010) Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease.J Neurochem. 113: 389-401

技术参数

产品应用 Flow Cytometry

产品类型单克隆抗体

推荐用于 Flow Cytometry

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Bio-Rad CD88抗体 MCA2456A647,Rat anti mouse CD88:Alexa Fluor647

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