BIO-RAD MCA1773 Mouse anti Rat CD61,Mouse anti Rat CD61

2024-10-22

Mouse anti Rat CD61

货号:MCA1773

规格:0.25 mg

价格:3043

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD61

物种:大鼠

宿主:小鼠

抗体亚型:IgG1

克隆号:F11

荧光染料:Purified

产品介绍
Mouse anti Rat CD61 antibody, clone F11recognizes the rat CD61 cell surface antigen, also known as the integrin b3 chain.CD61 is expressed by platelets, megakaryocytes and osteoclasts.Clone F11 has been shown to inhibit thein vitroattachment of osteoclasts to various proteins including vitronectin, fibrinogen and von Willebrand Factor (Sicket al.2009).
产品详情
Target SpeciesRat
Product FormPurified IgG - liquid
Species Cross-ReactivityTarget SpeciesCross Reactivity
HumanWeak
N.B. Antibody reactivity and working conditions may vary between species.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09%Sodium Azide
Carrier FreeYes
ImmunogenHuman myeloperoxidase
Fusion PartnersSpleen cells from immunized mice were fused with cells of the mouse X63 AG8-653 myeloma cell line
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/50
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Helfrich, M.H.et al.(1992) Integrins on rat osteoclasts: characterization of two monoclonal antibodies (F4 and F11) to rat beta 3.J Bone Miner Res. 7 (3): 345-51.2.Shankar, G.et al.(1993) Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts.J Cell Sci. 105 ( Pt 1): 61-8.3.Sick, E.et al.(2009) Activation of CD47 receptors causes histamine secretion from mast cells.Cell Mol Life Sci. 66: 1271-82.4.Wang, Z.et al.(2015) Microparticle levels after arterial injury andNOtherapy in diabetes.J Surg Res. pii: S0022-4804(15)00867-7

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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