BIO-RAD MCA1642EL Rat anti Human CD52:Low Endotoxin,Rat anti Human CD52:Low Endotoxin

2024-10-22

Rat anti Human CD52:Low Endotoxin

货号:MCA1642EL

规格:0.5 mg

价格:5041

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD52

物种:人

宿主:大鼠

抗体亚型:IgG2b

克隆号:YTH34.5

荧光染料:其它

产品介绍
Rat anti Human CD52 antibody, clone YTH34.5recognizes the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link (Xiaet al.1991).The apparent molecular mass of the native antigen on SDS-PAGE is 25-29 kDa, considerably reduced following N-glycanase treatment (Rowanet al.1998).CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.Humanized versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies (Deardenet al.2002;Pettittet al.2012).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
ImmunogenHuman monocytes
Preservative StabilisersNone present
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃ only.This product should be stored undiluted.Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/501/100
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed)STAR131AF1ml
文献
1.Klangsinsirikul, P.et al.(2002) Campath-1G causes rapid depletion of circulating host dendritic cells (DCs) before allogeneic transplantation but does not delay donor DC reconstitution.Blood. 99: 2586-91.2.Ratzinger, G.et al.(2003) Differential CD52 expression by distinct myeloid dendritic cell subsets: implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation.Blood. 101: 1422-9.3.Zand, M.S.et al.(2005) A renewable source of donor cells for repetitive monitoring of T- and B-cell alloreactivity.Am J Transplant. 5: 76-86.

技术参数

产品应用 Flow;Elisa

产品类型 Monoclonal Antibody

推荐用于 Flow;Elisa

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-40295.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价