Bio-Rad MCA1553 IL-2抗体,Rat anti Human Interleukin-2 antibody, clone MQ1-17H12-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad MCA1553 IL-2抗体,Rat anti Human Interleukin-2 antibody, clone MQ1-17H12

2024-10-22

Rat anti Human Interleukin-2 antibody, clone MQ1-17H12

货号：MCA1553

规格：0.5 mg

价格：3936

产品类型：流式抗体

品牌：Bio-Rad

抗原： IL-2

物种：人

宿主：大鼠

抗体亚型：IgG2a

克隆号：MQ1-17H12

荧光染料：Purified

产品介绍
Rat anti Human Interleukin-2 antibody, clone MQ1-17H12recognizes human interleukin-2 (IL-2), also known as T-cell growth factor or Aldesleukin. IL-2 is a 153 amino acid secreted cytokine produced by T-cells following antigenic or mitogenic stimulation. It plays a crucial role in T-cell proliferation and immune regulation.Rat anti Human Interleukin-2 antibody, clone MQ1-17H12 has been sucessfully used for the detection and measurement of native and recombinant human IL-2 using flow cytometry and ELISA where it ascts as the capture reagent in a very sensitive assay for IL-2 determination in human samples. IL-2 is used extensively for the treatment of patients with metastatic melanoma (Atkinset al.1999) and renal cancer with reproducible benificial effects (Rosenberg 2014). Monitoring of IL-2 levels in such patients is required for optimization of treatment regimens (Lotzeet al.1986). Rat anti Human Interleukin-2 antibody, clone MQ1-17H12 is also useful for evaluating levels of IL-2 in patients with autoimmune conditions including lupus erythematosus and rheumatoid arthritis where there may be an impaired ability to produce IL-2 (Talalet al.1983).
产品详情
Target Species	Human
Species Cross-Reactivity	Target Species	Cross Reactivity
Cynomolgus monkey	√
N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
BufferSolution	Phosphate buffered saline
Preservative Stabilisers	0.09%Sodium Azide
Carrier Free	Yes
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Regulatory	For research purposes only
Guarantee	12 monthsfrom date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√
Flow Cytometry1	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications fromthe originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. ¹Membrane permeabilization is required for this application. Bio-Rad recommend the use of Leucoperm™(Product CodeBUF09) for this purpose. Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. Flow CytometryUse 10ul of the suggested working dilution to label 1x106cells in 100ul.
文献
1. Garbe, Y.et al.(2011) Semiallogenic fusions of MSI(+) tumor cells and activated B cells induce MSI-specific T cell responses.BMC Cancer. 11: 410.2. Moncrieffe, H.et al.(2010) High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population.J Immunol. 185 (1): 134-43.

技术参数

产品应用 ELISA；Flow Cytometry

产品类型 Monoclonal Antibody

推荐用于 ELISA；Flow Cytometry

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Bio-Rad MCA1553 IL-2抗体,Rat anti Human Interleukin-2 antibody, clone MQ1-17H12

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