Human anti Cetuximab, clone AbD19815_hIgG1 HCA223 bio-rad ,Human anti Cetuximab, clone AbD19815_hIgG1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human anti Cetuximab, clone AbD19815_hIgG1 HCA223 bio-rad ,Human anti Cetuximab, clone AbD19815_hIgG1

2024-10-22

Human anti Cetuximab, clone AbD19815_hIgG1

货号：HCA223

规格：0.1 mg

价格：4522

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：Cetuximab

物种：人

宿主：人

抗体亚型：IgG1

克隆号：AbD19815_hIgG1

荧光染料：Purified

产品介绍
Human anti Cetuximab, clone AbD19815_hIgG1, is an anti-idiotypic antibody that binds specifically to cetuximab and inhibits the binding of the drug to its target, epidermal growth factor receptor (EGFR). It can be used in bioanalytical assays to measure the levels of cetuximab and biosimilar products in preclinical research and clinical trials.Human anti Cetuximab, clone AbD19815_hIgG1 is a fully human antibody and is particularly suited as a calibrator for immune response assays to measure the anti-drug antibody (ADA) levels in patient sera.Cetuximab (brand name Erbitux®) is a chimeric monoclonal antibody drug (IgG1/kappa) approved for treatment of KRAS wild-type metastatic colorectal cancers and squamous cell carcinoma of the head and neck. This therapeutic antibody is directed against EGFR and inhibits tumor cell proliferation by blocking the interaction of epidermal growth factor (EGF) with its receptor.
产品详情
Product Form	Human IgG1 antibody (lambda light chain) selected from the HuCAL® phage display library and expressed in a human cell line. This product is supplied as a liquid.
Preparation	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.01% Thiomersal
Immunogen	Cetuximab.
Affinity	The monovalent intrinsic affinity of this antibody was measured as KD= 10.5 nM by real time, label free molecular interaction analysis on immobilized cetuximab.
Approx. Protein ConcePurityntrations	Antibody concentration 0.5 mg/ml.
Acknowledgements	This product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. See bio-rad.com/en-us/trademarks for details.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
产品推荐
Description	Product Code	Applications	Pack Size
Hispec Assay Diluent	BUF049A	E	50ml

技术参数

产品应用 elisa

产品类型单克隆抗体

推荐用于 elisa

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Human anti Cetuximab, clone AbD19815_hIgG1 HCA223 bio-rad ,Human anti Cetuximab, clone AbD19815_hIgG1

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