Rabbit anti BAX antibody AHP2716 bio-rad,Rabbit anti BAX antibody

2024-10-22

Rabbit anti BAX antibody

货号:AHP2716

规格:50 µl

价格:2576

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti BAX antibodyrecognizes the Bcl-2-associated X protein (BAX) also known as Bcl-2 like protein 4. BAX together with BAK (BCL-2 antagonist or killer), another member of the Bcl-2 family, plays a key role in the intrinsic apoptosis pathway by inducing mitochondrial outer membrane permeabilization (MOMP) (Giansanti and Scovassi 2008). This event is aided by BID (BH3-interacting domain death agonist), which activates the two proteins and thereby facilitates the formation of homo- or heterodimers. Often in the literature, MOMP is regarded as the point of no return upon which a cell is committed to undergo apoptosis (Chipuket al.2006).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Antiserum PreparationAntiserum to BAX was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02% Sodium Azide50% Glycerol
ImmunogenSynthetic human BAX peptide
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/5001/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg

Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
文献
1.Giansanti, V. & Scovassi, A.I. (2008) Cell Death: A One-Way Journey to the Graveyard.The Open Biology Journal (1): 27-34.2.Chipuk, J.E.et al.(2006) Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario.Cell Death Differ. 13 (8): 1396-402

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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