Rabbit anti PP1 alpha (pThr320) antibody AHP2702 bio-rad,Rabbit anti PP1 alpha (pThr320) antibody

2024-10-22

Rabbit anti PP1 alpha (pThr320) antibody

货号:AHP2702

规格:50 µl

价格:3341

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:PP1 alpha (pThr320)

物种:其它

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti PP1 alpha (pThr320) antibodyrecognizes serine/threonine-protein phosphatase PP1-alpha catalytic subunit, also known as PPP1A, when phosphorylated at threonine 320. PP1 alpha is one of three catalytic subunits of protein phosphatase 1 (PP1). Catalytic subunits can form complexes with regulatory proteins to form distinct multimeric holoenzymes (Ceulemans, H. & Bollen, M. 2004). PP1 activity is crucial for cell cycle progression. PP1 dephosphorylates many substrates target including retinoblastoma protein (Rb) (Durfee, T. et al. 1993). Phosphorylation of PP1 alpha on residue threonine 320 is performed by Cyclin-dependent kinase 1 (CDC2) kinase and leads to inhibition of its activity (Kwon, Y.G. el al. 1997).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Antiserum PreparationAntiserum to PP1 alpha (pThr320) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02% Sodium Azide50% Glycerol
ImmunogenPhospho specific-peptide corresponding to residues surrounding threonine 320 of human PP1 alpha
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/5001/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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