Rabbit anti VAV1 (pTyr174) antibody AHP2691 bio-rad,Rabbit anti VAV1 (pTyr174) antibody

2024-10-22

Rabbit anti VAV1 (pTyr174) antibody

货号:AHP2691

规格:50 µl

价格:3613

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:VAV1 (pTyr174)

物种:其它

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti VAV1 (pTyr174) antibodyrecognizes VAV1, also known as vav guanine nucleotide exchange factor 1 when phosphorylated at tyrosine 174. VAV1 is a member of the Vav family of guanine nucleotide exchange factors (GEFs). GEFs are involved in the activation of small GTPases which play a role in many signaling pathways. Potential substrates for VAV1 activity include Rac1, Cdc42 RhoA and RhoG. VAV1 is phosphorylated on tyrosine 174 leads to conformational changes and activation of VAV1 (Katzav 2015).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Antiserum PreparationAntiserum to VAV1 (pTyr174) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02% Sodium Azide50% Glycerol
ImmunogenPhospho specific-peptide corresponding to residues surrounding tyrosine 174 of human VAV1
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/5001/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg

Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
文献
1.Katzav, S. (2015) Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer.Oncotarget. 6 (30): 28731-42.

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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