Rabbit anti BRCA1 (pSer988) antibody AHP2561 bio-rad,Rabbit anti BRCA1 (pSer988) antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti BRCA1 (pSer988) antibody AHP2561 bio-rad,Rabbit anti BRCA1 (pSer988) antibody

2024-10-22

Rabbit anti BRCA1 (pSer988) antibody

货号：AHP2561

规格：50 µl

价格：3613

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：BRCA1 (pSer988)

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti BRCA1 (pSer988) antibodyrecognizes BRCA1, also known as breast cancer type 1 susceptibility protein and RING finger protein 53, when phosphorylated at serine 988. Breast cancer susceptibility genes BRCA1 and BRCA2 are associated with hereditary breast and ovarian cancers. BRCA1 is a tumor suppressor gene encoding an E3 ubiquitin protein ligase that plays a major role in DNA damage repair (Royet al.2011).BRCA1 is also involved in the regulation of multiple processes including transcription and cell cycle progression. BRCA1 co-localizes with Chk2 in nuclear foci, in response to DNA damage BCRA1 is phosphorylated at serine 988 by Chk2. This phosphorylation event results in the release and dispersion of BRCA1 and is suggested to be important for the function of BRCA1 in the DNA damage response (Leeet al.2000).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to BRCA1 (pSer988) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02% Sodium Azide50% Glycerol
Immunogen	Phospho specific-peptide corresponding to residues surrounding serine 988 of human BRCA1
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/500	1/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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Rabbit anti BRCA1 (pSer988) antibody AHP2561 bio-rad,Rabbit anti BRCA1 (pSer988) antibody

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