Bio-Rad BAX抗体 AHP2421,Rabbit anti BAX

2024-10-22

Rabbit anti BAX

货号:AHP2421

规格:0.1 mg

价格:2576

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:BAX

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍

Rabbit anti BAX antibodyrecognizes the Bcl-2-associated X protein (BAX) also known as Bcl-2 like protein 4. BAX together with BAK (BCL-2 antagonist or killer), another member of the Bcl-2 family, plays a key role in the intrinsic apoptosis pathway by inducing mitochondrial outer membrane permeabilization (MOMP) (Giansanti and Scovassi 2008). This event is aided by BID (BH3-interacting domain death agonist), which activates the two proteins and thereby facilitates the formation of homo- or heterodimers. Often in the literature, MOMP is regarded as the point of no return upon which a cell is committed to undergo apoptosis (Chipuket al.2006).

产品详情

Target Species

Human

Species Cross-Reactivity

Target Species Cross Reactivity

Mouse √

Rat √

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

Preparation

Purified IgG prepared by affinity chromatography

AntiserumPreparation

Antiserum to BAX was raised by repeated immunisation of rabbits with highly purified antigen

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.1% Sodium Azide (NaN3)0.2% Gelatin

Immunogen

Peptide mapping to the amino terminus of human BAX

Approx. Protein Concentrations

IgG concentration 0.2 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

应用

Application Name

Verified

Min Dilution

Max Dilution

Western Blotting

1/400

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • Rabbit anti BAX recognizes a band of approximately 23 kDa when run under reducing conditions

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文献

References for BAX antibody

1.Olejnik, J.et al.(2013) Ebola virus does not block apoptotic signaling pathways.J Virol. 87 (10): 5384-96.

技术参数

产品应用 WB

产品类型 Polyclonal Antibody

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