Bio-Rad VPS34抗体 AHP2224,Rabbit anti VPS34

2024-10-22

Rabbit anti VPS34

货号:AHP2224

规格:0.1 mg

价格:6375

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:VPS34

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍

Rabbit anti VPS34 antibodyrecognises Phosphatidylinositol 3-kinase catalytic subunit type 3, also known as VPS34 (vacuolar protein sorting 34), PI3-kinase type 3 or PIK3C3. VPS34 is a ubiquitously expressed class III PI3K (phosphoinositide 3-kinase), and member of the PI3/PI4-kinase family, which utilizes phosphatidylinositol (PtdIn) as a substrate, and functions as the catalytic subunit of the PI3K complex.VPS34 plays a role in the transport of lysosomal enzyme precursors to lysosomes, and in endocytosis and vesicular trafficking, and has been strongly implicated as a regulator of autophagy, forming a multi-protein complex with the proautophagic tumor suppressors Beclin1/Atg6, Bif-1, and UVRAG, in the initiation of autophagosome formation. Distinct complexes of VPS34 regulates endocytic processes vital for late-stage autophagosome-lysosome fusion.

产品详情

Target Species

Human

Species Cross-Reactivity

Target Species Cross Reactivity

Mouse √

Rat √

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

AntiserumPreparation

Antiserum to human VSP34 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

<0.1% Sodium Azide (NaN3)

Immunogen

KLH conjugated synthetic peptide corresponding to amino acids 22-34 of human VPS34, The corresponding sequence is identical in mouse and rat.

Approx. Protein Concentrations

IgG concentration 1.0mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

应用

Application Name

Verified

Min Dilution

Max Dilution

Immunofluorescence

1/100

Western Blotting

2.0

4.0ug/ml

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • AHP224 detects a band of approximately 105kDa in HEK-293T cell lysates.

可用二抗

Description

Product Code

Applications

Pack Size

Goat anti Rabbit IgG (Fc):Biotin

STAR121B

E WB

1 mg

Goat anti Rabbit IgG (Fc):FITC

STAR121F

F

1 mg

Goat anti Rabbit IgG (Fc):HRP

STAR121P

E WB

1 mg

Goat anti Rabbit IgG (H/L):HRP

STAR124P

C E WB

1 mg

Sheep anti Rabbit IgG:FITC

STAR34B

C F

1 mg

Sheep anti Rabbit IgG:RPE

STAR35A

F

1 ml

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技术参数

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产品类型 Polyclonal Antibody

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