Bio-Rad AHP1924 Annexin V ,Rabbit anti Human Annexin V antibody

2024-10-22

Rabbit anti Human Annexin V antibody

货号:AHP1924

规格:0.1 mg

价格:5636

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Annexin V

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human Annexin V antibody(AHP1924) recognizes human annexin V (ANXA5), otherwise known as lipocortin V, a calcium-dependent phospholipid-binding protein and member of the annexin family, which binds with high affinity and selectivity to phosphatidylserine (PS).The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell, by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death.Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus, recurrent spontaneous abortions and systemic sclerosis.
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Antiserum Preparation

Antiserum to human ANXA5 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

<0.1% Sodium Azide (NaN3)

Immunogen

6xHis-tagged full-length recombinant human ANXA5 (NP_001145.1).
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA
Western Blotting1/250
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
数据

Human tonsil lysate probed with Rabbit anti Human Annexin V (AHP1924)
相关试剂
DescriptionProduct CodeApplicationsPack Size
TidyBlot Western Blot Detection Reagent:HRPSTAR209PWB0.5 mL
文献
1. Moss, S.E. & Morgan, R.O. (2004) The annexins.Genome Biol. 5 (4): 219.

技术参数

产品应用 E;WB

产品类型 Polyclonal Antibody

推荐用于 E;WB

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