Rabbit anti Caspase-7 (N-Terminal) antibody AHP1788 bio-rad,Rabbit anti Caspase-7 (N-Terminal) antibody

2024-10-22

Rabbit anti Caspase-7 (N-Terminal) antibody

货号:AHP1788

规格:0.1 mg

价格:3588

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Caspase-7 (N-Terminal)

物种:其它

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Caspase-7 (N-Terminal) antibodyrecognizes an epitope within the N-Terminal region (NT) of Caspase-7, a ~35 kDa cysteine protease, otherwise known as ICE-like Apoptotic Protease 3 (ICE-LAP3).Caspase-7, a member of the ICE/Ced-3 subfamily, is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits. Evidence that activation of Caspase-7 occurs during cell death induced by the cytokine death receptors Fas/APO-1 and the receptor of tumour necrosis factor (TNFR-1), coupled with the fact that granzyme-B activated Caspase-7 cleaves the nuclear enzyme poly (ADP-ribose) polymerase (PARP), suggests an important role for Caspase-7 in both cytokine-mediated and granzyme-B mediated apoptosis pathways.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Species Cross-ReactivityTarget SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Antiserum PreparationAntiserum to human Caspase-7 (NT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02% Sodium Azide (NaN3).
ImmunogenA 16 amino acid peptide from human Caspase-7 amino-terminus.
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Immunohistology - Frozen10ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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