Bio-Rad Desmin抗体 AHP2116,Goat anti Human Desmin (C-Terminal)

2024-10-22

Goat anti Human Desmin (C-Terminal)

货号:AHP2116

规格:0.1 mg

价格:5083

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Desmin

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍

Goat anti Human Desmin antibodyrecognizes an epitope within the C-terminal (CT) region of human Desmin, a type III intermediate filament (IF), localized near the Z line in sacromeres of skeletal, smooth and cardiac muscle tissue.Desmin plays an essential role in the architecture of muscle cells, connecting the Z-disk to the subsarcolemmal cytoskeleton, and the contractile apparatus to the, mitochondria, cell nucleus and post-synaptic areas of motor endplates. Desmin is an early indicator for muscle tissue in embryogenesis, and a marker for tumours of myogenic origin. Mutations in the Desmin gene, are responsible for the neuromuscular disorder known as desmin-related cardio skeletal myopathy (CSM), characterized by skeletal muscle weakness.

产品详情

Target Species

Human

Species Cross-Reactivity

Target Species Cross Reactivity

Dog Expected from Sequence

Bovine Expected from Sequence

Mouse √

Rat √

Pig √

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

AntiserumPreparation

Antiserum to human Desmin (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin

Immunogen

Synthetic peptide sequence C-RDGEVVSEATQQQHE from the C-Terminal region of Desmin (NP_001918.3).

Approx. Protein Concentrations

IgG concentration 0.5 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA

1/2000

Immunohistology -Paraffin1

3.0

6.0ug/ml

Western Blotting

0.1

0.3ug/ml

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.1This product requires heat-mediated antigen retrieval prior to staining of paraffin sections. Sodium citrate buffer pH6.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Histology Positive Control Tissue
  • Human prostate
  • Western Blotting
  • Goat anti Human Desmindetects a band of approximately 55kDa in human skeletal muscle cell lysates.

可用二抗

Description

Product Code

Applications

Pack Size

Rabbit anti Goat IgG (Fc):FITC

STAR122F

F

1 mg

Rabbit anti Goat IgG (Fc):HRP

STAR122P

C E WB

1 mg

相关产品

Description

Product Code

Applications

Pack Size

Antigen Retrieval Buffer, pH8.0

BUF025A

P

500 ml

技术参数

产品应用 E ;P*; WB

产品类型 Polyclonal Antibody

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