Goat anti Human LNK antibody AHP1003 bio-rad,Goat anti Human LNK antibody

2024-10-22

Goat anti Human LNK antibody

货号:AHP1003

规格:0.1 mg

价格:5083

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:LNK

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human LNK antibodyrecognizes human SH2B adapter protein 3, also known as Lymphocyte-specific adapter protein Lnk or Lymphocyte adapter protein. LNK is a 575 amino acid SH2B adapter protein containing a single PH domain and a single SH2 domain. Goat anti Human LNK antibody binds to an epitope within the N-terminal region of LNK, which regulates cytokine receptor-mediated and growth factor pathways, and plays an essential role in B cell lymphopoiesis.LNK mRNA is preferentially expressed in lymph node and spleen lymphocytes and the expression of LNK in vascular endothelial cells (ECs), increases in response to TNFα. LNK acts as a negative regulator of the pro-inflammatory molecules VCAM-1 and E-selectin induced by TNFα, modulation of P13-kinase and MAPK ERK1/2 activity. LNK is also involved in the negative regulation of Thrombopoietin-mediated cell proliferation and endomitosis in hematopoietic cell lines.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationAntisera to LNK (NT) were raised by repeated immunisation of Goat with highly purified antigen.<br Purified IgG prepared by affinity chromatography.
Buffer SolutionTRIS buffered saline
Preservative Stabilisers0.02% Sodium Azide0.5% Bovine Serum Albumin
ImmunogenPeptide sequence NGPALQPSSPC from LNK amino-terminus.
Approx. Protein ConcentrationsIgG concentration 0.5mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting0.31.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Rabbit anti Goat IgG (Fc):FITCSTAR122FF100 Tests
Rabbit anti Goat IgG (Fc):HRPSTAR122PC,E,WB100 Tests

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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