Rabbit anti Human Beclin-1 antibody AHP1009 bio-rad,Rabbit anti Human Beclin-1 antibody

2024-10-22

Rabbit anti Human Beclin-1 antibody

货号:AHP1009

规格:0.1 mg

价格:4692

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Beclin-1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human Beclin-1 antibodyrecognizes an epitope within the N-terminal region of Beclin-1, a ~52 kDa coiled-coil protein which shares structural homology with the yeast autophagy gene apg6/vps30.The ability of cells to undergo bulk degradation of endogenous proteins through an autophagosomic-lysosomal pathway, termed autophagy or Type II cell death, is important in the control of cell growth and development. Studies have identified Beclin-1 as a Bcl-2 interacting mammalian gene which not only mediates autophagy, but also functions as a tumour suppressor, being expressed at reduced levels in human breast carcinoma, and may also play a role in defense against viral infection. An increasing number of studies have revealed an interaction between proteins which induce autophagy and those involved in apoptosis and in some instances apoptosis may be dependant upon or delayed by autophagy.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Antiserum PreparationAntisera to human Beclin-1 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02%Sodium Azide (NaN3)
ImmunogenA 17 amino acid peptide located near human Beclin-1 amino-terminus.
Approx. Protein ConcentrationsIgG concentration 1.0mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting0.5ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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