Sheep anti Rat endothelin B receptor antibody AAR43 bio-rad,Sheep anti Rat endothelin B receptor antibody

2024-10-22

Sheep anti Rat endothelin B receptor antibody

货号:AAR43

规格:0.1 mg

价格:2992

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:大鼠

宿主:Sheep

抗体亚型:IgG

荧光染料:Purified

产品介绍
Sheep anti Rat endothelin B receptor antibodyrecognizes an epitope within the C-terminal (CT) region of endothelin B receptor (ET-B), a widely distributed transmembrane protein and member of the G-protein coupled receptor 1 family, which acts as a non-specific receptor for endothelin 1, 2, and 3, and mediates its action by G protein association and activation of a phosphatidylinositol-calcium second messenger system. Sheep anti Rat endothelin B receptor antibody (AAR43) recognizes epitopes on the cytoplasmic side of the receptor and therefore the cell membrane must be permeable to the antibody. AAR43 does not block the binding of endothelins.Sheep anti Rat endothelin B receptor antibody (AAR43) is suitable for use in immunocytochemistry on acetone fixed cells.
产品详情
Target SpeciesRat
Product FormPurified IgG - liquid
Species Cross-ReactivityTarget SpeciesCross Reactivity
Mouse
Human
N.B. Antibody reactivity and working conditions may vary between species.
Antiserum PreparationAntiserum to rat ET-B (CT) was raised by repeated immunisation of sheep with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
ImmunogenKeyhole limpet haemocyanin (KLH) conjugated C-terminal peptide KANDHGYDNFRSSNN corresponding to amino acids 424 to 437 of rat endothelin B receptor.
Approx. Protein ConcentrationsIgG concentration 1.41mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Immunocytochemistry
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Rabbit anti Sheep IgG (H/L):Biotin5184-2304F,E0.5mg
Donkey anti Sheep/Goat IgG:DyLight®488STAR88D488GAF,IF0.5mg

技术参数

产品应用 if

产品类型 Polyclonal Antibody

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