Bio-Rad Laminin抗体 5620-0436,Mouse anti Human Laminin Alpha 5-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad Laminin抗体 5620-0436,Mouse anti Human Laminin Alpha 5

2024-10-22

Mouse anti Human Laminin Alpha 5

货号：5620-0436

规格：50 µl

价格：5058

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：Laminin

物种：人

宿主：小鼠

抗体亚型：IgG2a

荧光染料：其它

产品介绍
Mouse anti Human Laminin Alpha 5 antibody, clone 4C7recognizes the laminin alpha 5 chain also known as Laminin-10 subunit alpha, Laminin-11 subunit alpha or Laminin-15 subunit alpha. Laminin is a complex glycoprotein composed of three polypeptide chain complexes. Laminin alpha 5 is expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta, there is little or no expression in brain and liver.
产品详情
Target Species	Human
Species Cross-Reactivity	Target Species	Cross Reactivity
	Rat	×
	Mouse	×
	N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Ascites - liquid
Preservative Stabilisers	<0.1% Sodium Azide (NaN₃)
Immunogen	Purified human laminin.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√
Immunofluorescence	√
Immunoprecipitation	√
Western Blotting	×
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
文献
1.Engvall, E.et al.(1986) Mapping of domains in human laminin using monoclonal antibodies: localization of the neurite-promoting site.J Cell Biol. 103 (6 Pt 1): 2457-65.2.Engvall, E.et al.(1990) Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.Cell Regul. 1 (10): 731-40.3.Ido, H.et al.(2006) Probing the integrin-binding site within the globular domain of laminin-511 with the function-blocking monoclonal antibody 4C7.Matrix Biol. 25 (2): 112-7.4.Chang, C.et al.(2015) A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells.Genes Dev. 29 (1): 1-6.5.Zamurs, L.et al.(2013) Chain-specific antibodies for laminin-511.Growth Factors. 31 (6): 209-19.6.Tiger, C.F.et al.(1997) Presence of laminin alpha5 chain and lack of laminin alpha1 chain during human muscle development and in muscular dystrophies.J Biol Chem. 272 (45): 28590-5.7.Pouliot, N. & Kusuma, N. (2013) Laminin-511: a multi-functional adhesion protein regulating cell migration, tumor invasion and metastasis.Cell Adh Migr. 7 (1): 142-9.8.Schaff, M.et al.(2013) Integrin α6β1 is the main receptor for vascular laminins and plays a role in platelet adhesion, activation, and arterial thrombosis.Circulation. 128 (5): 541-52.View The Latest Product References

技术参数

产品应用 E; IF; IP

产品类型 Monoclonal Antibody

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Bio-Rad Laminin抗体 5620-0436,Mouse anti Human Laminin Alpha 5

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