Sheep anti Human ceruloplasmin antibody bio-rad,Sheep anti Human ceruloplasmin antibody

2024-10-22

Sheep anti Human ceruloplasmin antibody

货号:1940-0004

规格:1 ml

价格:4378

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:Sheep

抗体亚型:IgG

荧光染料:Purified

产品介绍
Sheep anti Human ceruloplasmin antibodydetects ceruloplasmin, a ~132kDa metalloprotein that is secreted into the plasma by liver hepatocytes and activated monocytes/macrophages. Ceruloplasmin functions in copper transport, iron homeostasis, antioxidant defence, angiogenesis and coagulation.Deficiency in ceruloplasmin is termed aceruloplasminemia, an autosomal recessive disorder which leads to iron accumulation and tissue damage, in particular in the brain and visceral organs. Clinical features include retinal degeneration, diabetes mellitus and neurological disturbances.Elevated plasma ceruloplasmin has been shown to pose an increased risk in atherosclerosis and myocardial infarction.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography
Buffer SolutionPhosphate buffered saline
ImmunogeHighly pure human ceruloplasmin.
Approx. Protein ConcentrationsIgG concentration 5.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA0.5 µg/ml1 µg/ml
Immunohistology - Frozen10 µg/ml20 µg/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Donkey anti Sheep/Goat IgG:DyLight®488STAR88D488GAF,IF0.1mg
Rabbit anti Sheep IgG (H/L):Biotin5184-2304E,WB1.5 ml
文献
1De Paula, M.L.et al.(2014) The PTEN inhibitor bisperoxovanadium enhances myelination by amplifying IGF-1 signaling in rat and human oligodendrocyte progenitors.Glia. 62 (1): 64-77.2。Preisner, A.et al.(2015) Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination.Acta Neuropathol. 130 (2): 247-61.3.Kuroda, M.et al.(2017) Peripherally derived FGF21 promotes remyelination in the central nervous system.J Clin Invest. 127 (9): 3496-509.

技术参数

产品应用 Elisa

产品类型 Polyclonal Antibody

推荐用于 Elisa

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-43530.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价