Recombinant Human IFN-γ
货号:300-02-100,300-02-1000,300-02-20,300-02-250,300-02-500
规格:100ug,1mg,20ug,250ug,500ug
价格:1418,9379,582,4092,6082
产品类型:细胞因子添加物
品牌:PeproTech
产品描述:IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues.来源:E.coli别名:Immune Interferon, type II interferon, T cell interferon, MAF氨基酸序列:MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Assay #1:Determined by its ability to induce STAT1/STAT2 activation in Human COLO 205 ISRE LUC reporter cells.Assay #2:TheED50determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.Calculated Molecular Weight:16.8 kDaAccession Number:P01579.1Gene ID:3458交叉反应:Bacteria,Fish + Virus,Human,Human + Bacteria,Human + Hamster,Human + Mouse,Human + Virus,Mandarin Fish,Monkey,Mouse,Pig,Rabbit,Rat原产地:USA仅用于科研,不能用于临床和诊断。 |
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