Animal-Free Recombinant Human Epiregulin
货号：AF-100-04-100,AF-100-04-1000,AF-100-04-25,AF-100-04-250,AF-100-04-5,AF-100-04-500
规格：100ug,1mg,25ug,250ug,5ug,500ug
价格：12700,50820,2830,22230,1250,33030
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant Human Epiregulin is a 5.6 kDa monomeric protein, containing 50 amino residues, which corresponds to the mature secreted Epiregulin sequence.Manufactured using all Animal-Free reagents.来源：E.coli别名：EREG氨基酸序列：MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL纯度：≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性：Determined by its ability to stimulate the proliferation of mouse Balb/3T3 cells. The expectedED50is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106units/mg.Calculated Molecular Weight:5.6 kDaAccession Number:O14944Gene ID:2069 |
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