CD26 (Soluble) Human ELISA Kit ELISA试剂盒,CD26 (Soluble) Human ELISA Kit/人CD26（可溶）ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

CD26 (Soluble) Human ELISA Kit ELISA试剂盒,CD26 (Soluble) Human ELISA Kit/人CD26（可溶）ELISA试剂盒

2024-10-23

CD26 (Soluble) Human ELISA Kit/人CD26（可溶）ELISA试剂盒

货号：BMS235,BMS235TEN

规格：96 Tests,10X96 Tests

价格：5888,35475

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	7.3 ng/mL
检测范围	15.6-500 ng/mL
样本类型/体积	血清 20 μL 上清液 20 μL
操作时间	1 hr 20 min
测试时间	4 hr 10 min
Homogenous (no wash)	No
批间变异系数（CV）	9.1%
批内变异系数（CV）	4.6%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	10 x 96 tests
组份	- 预包被96孔板 - 标准品 - 样品稀释液 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CD26
Protein aliases	ADABP, ADCP-2, Adenosine deaminase complexing protein 2, CD26, Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, dipeptidyl-peptidase 4, dipeptidylpeptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPP IV, T-cell activation antigen CD26, TP103
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	ADABP, ADCP2, CD26, DPP4, DPPIV, TP103
Gene ID	(Human) 1803
Gene symbol	DPP4
UniProt ID	(Human) P27487

The Human Soluble CD26 ELISA quantitates Hu sCD26 in human serum, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu sCD26.人可溶性CD26 ELISA可以定量人血清或细胞培养基中的人sCD26。该检测试剂盒将只识别天然和重组人sCD26。Principle of the method 方法原理The Human sCD26 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.人sCD26固相夹心ELISA（酶联免疫吸附测定）用于测量匹配的抗体对之间结合的靶标量。已在提供的微孔板的孔中预包被了靶标特异性抗体。然后将样品，标准液或质控品添加到这些孔中，并与固定的（捕获）抗体结合。通过添加第二（检测）抗体形成三明治，添加底物溶液，该底物溶液与酶-抗体-靶标复合物反应以产生可测量的信号。该信号的强度与原始样品中存在的靶标浓度成正比。Rigorous validation 严格验证Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.此ELISA试剂盒的每个制造批次均经过质量测试，其标准包括敏感性，特异性，精密度和批次间一致性。有关验证的更多信息，请参见手册。Target information 靶标信息CD26 (dipeptidyl peptidase IV, DPP IV), adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family. CD26 is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti CD3-induced IL - 2 production. CD26 identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. Further, CD26 is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Alterations in CD26 peptidase activity are characteristic of malignant transformation, and the enzymatic activity increases dramatically with tumor grade and severity. CD26 is expressed in various blood cell types, but also in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.CD26（二肽基肽酶IV，DPP IV，腺苷脱氨酶（ADA）结合蛋白）是属于脯氨酰寡肽酶家族的同型二聚体非典型丝氨酸蛋白酶。 CD26在淋巴细胞上表达，并在T细胞活化过程中被上调。 CD26还可以在活化的B细胞和自然杀伤细胞上表达，并在上皮细胞上大量表达。 CD26与多种生物学功能有关，包括T细胞活化，细胞与细胞外基质（如纤连蛋白或胶原蛋白）的粘附以及HIV感染。使用该抗体的CD26交联可显着增强抗CD3诱导的IL-2的产生。 CD26与腺苷脱氨酶复合蛋白2和T细胞活化抗原CD26相同。此外，CD26是内在的膜糖蛋白和丝氨酸外肽酶，其从多肽的N-末端切割X-脯氨酸二肽。 CD26肽酶活性的改变是恶性转化的特征，并且酶活性随肿瘤等级和严重性而急剧增加。 CD26在各种血细胞类型中表达，但也在与激活的成纤维细胞组织学相关的细胞中表达。在类风湿性关节炎和系统性红斑狼疮期间，循环单核细胞和CD4 + T细胞的CD26密度发生了变化。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

数据：

CD26 (Soluble) Human ELISA KitRepresentative standard curve for Human CD26 ELISA

技术参数

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CD26 (Soluble) Human ELISA Kit ELISA试剂盒,CD26 (Soluble) Human ELISA Kit/人CD26（可溶）ELISA试剂盒

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