VEGF Receptor 1 (Soluble) Human ELISA Kit ELISA试剂盒,VEGF Receptor 1 (Soluble) Human ELISA Kit/人VEGF 受体 1 (可溶)ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

VEGF Receptor 1 (Soluble) Human ELISA Kit ELISA试剂盒,VEGF Receptor 1 (Soluble) Human ELISA Kit/人VEGF 受体 1 (可溶)ELISA试剂盒

2024-10-23

VEGF Receptor 1 (Soluble) Human ELISA Kit/人VEGF 受体 1 (可溶)ELISA试剂盒

货号：BMS268-3,BMS268-3TEN

规格：96 Tests,10X96 Tests

价格：6120,35475

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.03 ng/mL
检测范围	0.16-10.0 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	3 hr 30 min
Homogenous (no wash)	No
批间变异系数（CV）	5.1%
批内变异系数（CV）	5.5%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	10 x 96 tests
组份	- 预包被96孔板 - 标准品 - 样品稀释液 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	VEGF Receptor 1
Protein aliases	FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR-1
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	FLT, FLT-1, FLT1, FRT, VEGFR-1, VEGFR1
Gene ID	(Human) 2321
Gene symbol	FLT1
UniProt ID	(Human) P17948

The Human Vascular Endothelial Growth Factor Receptor 1 (Hu VEGFR1) ELISA quantitates Hu VEGFR1 in human serum, plasma, buffered solution, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu VEGFR1.人血管内皮生长因子受体1（人 VEGFR1）ELISA定量了人血清，血浆，缓冲液或细胞培养基中的人VEGFR1。该检测试剂盒将专门识别天然和重组人VEGFR1。Principle of the method 方法原理The Human VEGFR1 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.人VEGFR1固相夹心ELISA（酶联免疫吸附测定）用于测量匹配的抗体对之间结合的靶标量。已在提供的微孔板的孔中预包被了靶标特异性抗体。然后将样品，标准液或质控品添加到这些孔中，并与固定的（捕获）抗体结合。通过添加第二（检测）抗体形成三明治，添加底物溶液，该底物溶液与酶-抗体-靶标复合物反应以产生可测量的信号。该信号的强度与原始样品中存在的靶标浓度成正比。Rigorous validation 严格验证Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.此ELISA试剂盒的每个制造批次均经过质量测试，其标准包括敏感性，特异性，精密度和批次间一致性。有关验证的更多信息，请参见手册。Target information 靶标信息Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.酪氨酸蛋白激酶，可作为VEGFA，VEGFB和PGF的细胞表面受体，在胚胎脉管系统的发育，血管新生，细胞存活，细胞迁移，巨噬细胞功能，趋化性和癌细胞的调节中起着至关重要的作用。通过抑制内皮细胞的过度增殖，可作为胚胎血管生成的负调节剂发挥重要作用。可以促进成年后内皮细胞的增殖，存活和血管生成。其促进细胞增殖的功能似乎是细胞类型特异性的。促进PGF介导的内皮细胞增殖，某些类型癌细胞的增殖，但不促进正常成纤维细胞（体外）的增殖。对VEGFA有很高的亲和力，蛋白激酶活性相对较低；通过限制游离VEGFA的量并防止其与KDR结合，其可以作为VEGFA信号转导的负调节剂。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

数据：

VEGF Receptor 1 (Soluble) Human ELISA KitRepresentative standard curve for Human VEGF Receptor 1 ELISA

技术参数

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VEGF Receptor 1 (Soluble) Human ELISA Kit ELISA试剂盒,VEGF Receptor 1 (Soluble) Human ELISA Kit/人VEGF 受体 1 (可溶)ELISA试剂盒

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