Human CDNF ELISA Kit ELISA试剂盒,Human CDNF ELISA Kit/人CDNF ELISA试剂盒

2024-10-23

Human CDNF ELISA Kit/人CDNF ELISA试剂盒

货号:EH101RB,EH101RBX5,EH101RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

6 pg/mL

检测范围6-1,500 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCDNF
Protein aliasesarginine-rich, mutated in early stage tumors-like 1, ARMET-like protein 1, Cerebral dopamine neurotrophic factor, Conserved dopamine neurotrophic factor

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesARMETL1, CDNF
Gene ID(Human) 441549
Gene symbolCDNF
UniProt ID(Human) Q49AH0
Human CDNF quantitates human CDNF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CDNF.人CDNF定量测定血清,血浆,上清液中的人CDNF。 该检测试剂盒将专门识别天然和重组人CDNF。Target information 靶标信息The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.保守的多巴胺神经营养因子(CDNF)是多巴胺能神经元的神经营养因子,与中脑星形胶质细胞衍生的神经营养因子高度同源。 出乎意料的是,CDCF在组织(例如心脏,骨骼肌和睾丸)中的表达水平高于大脑。 与神经胶质细胞系衍生的神经营养因子(GDNF)相似,CDNF可以预防帕金森病大鼠模型中6-羟胺(6 OHDA)引起的多巴胺能神经元变性。 此外,CDNF能够恢复多巴胺能神经功能并防止黑质中多巴胺能神经元变性,这表明CDNF可能适合治疗帕金森病。 已知存在至少两种CDNF同工型。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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