Human ErbB4 ELISA Kit ELISA试剂盒,Human ErbB4 ELISA Kit/人ErbB4 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human ErbB4 ELISA Kit ELISA试剂盒,Human ErbB4 ELISA Kit/人ErbB4 ELISA试剂盒

2024-10-23

Human ErbB4 ELISA Kit/人ErbB4 ELISA试剂盒

货号：EH175RB,EH175RBX5,EH175RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.2 ng/mL
检测范围	0.2-50 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	ErbB4
Protein aliases	4ICD, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, ERBB4 intracellular domain, ERBB4 transcript variant I12DEL, ERBB4 transcript variant I20DEL, human epidermal growth factor receptor 4, p180erbB4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, s80HER4, Tyrosine kinase-type cell surface receptor HER4, v-erb-a erythroblastic leukemia viral oncogene homolog 4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	ALS19, ERBB4, HER4, p180erbB4
Gene ID	(Human) 2066
Gene symbol	ERBB4
UniProt ID	(Human) Q15303

Human ErbB4 quantitates human ErbB4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ErbB4.人ErbB4定量检测血清，血浆，上清液中的人ErbB4。该检测试剂盒将只识别天然和重组人ErbB4。Target information 靶标信息ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases). ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself. Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum. Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361. Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3. ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.ErbB 4（Her-4，c-erbB-4，v-erbB-4）是I类受体激酶家族的成员。蛋白激酶家族拥有500多种基因产物，是真核生物中最大的蛋白家族之一。根据其酪氨酸（PTK）或丝氨酸/苏氨酸（STK）激酶催化域的序列比较，该家族已分为8大类。 ErbB 4被神经调节蛋白和NTAK（神经和胸腺的ErbB激酶激活剂）激活。 ErbB 4是调蛋白的受体，能够介导HGL刺激的酪氨酸磷酸化。与其他蛋白激酶一样，ErbB 4介导真核细胞中的大多数信号转导，调节细胞代谢，转录，细胞周期进程，细胞骨架重排和细胞运动，细胞凋亡和分化。 ErbB 4最主要在几种乳腺癌细胞系中以及正常骨骼肌，心脏，垂体，大脑和小脑中表达。发现乳腺癌细胞系T47-D，MDA-MB-453，BT-474和H3396的mRNA水平最高，在MCF-7，MDAMB-330和MDA-MB-361中处于中等水平。在某些乳腺肿瘤细胞系（例如MDA-MB-231，MDA-MB-157，MDA-MB-468和SKBR-3）中，ErbB 4的表达较低或不存在。已经发现在某些人肿瘤细胞系中ErbB 4水平升高，表明它可能在某些恶性肿瘤中起作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

技术参数

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-46606.htm

特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系删除，本平台不提供信息存储服务。

Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.

产品询价需求提交

Human ErbB4 ELISA Kit ELISA试剂盒,Human ErbB4 ELISA Kit/人ErbB4 ELISA试剂盒

相关推荐