Human FOLR3 ELISA Kit ELISA试剂盒,Human FOLR3 ELISA Kit/人FOLR3 ELISA试剂盒

2024-10-23

Human FOLR3 ELISA Kit/人FOLR3 ELISA试剂盒

货号:EH201RB,EH201RBX5,EH201RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

32 pg/mL

检测范围32-8,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameFOLR3
Protein aliasesFolate receptor 3, folate receptor 3 (gamma), Folate receptor gamma, FR-gamma

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesFOLR3, FR-G, FR-gamma, gamma-hFR
Gene ID(Human) 2352
Gene symbolFOLR3
UniProt ID(Human) P41439
Human FOLR3 quantitates human FOLR3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human FOLR3.人FOLR3定量检测血清,血浆,上清液中的人FOLR3。 该测定法将只识别天然和重组人FOLR3。Target information 靶标信息Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydrofolate into the cell. The folate receptors consist of five members, alpha, beta, gamma, gamma' (which is produced by alternative splicing) and delta. beta-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. gamma-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of delta-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The alpha isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.叶酸是必需的维生素,必须通过哺乳动物的肠道吸收从食物中摄取。叶酸和还原的叶酸衍生物与叶酸受体(FR)家族结合,后者介导5-甲基四氢叶酸向细胞内吞。叶酸受体由五个成员组成:α,β,γ,γ'(通过选择性剪接产生)和δ。 β-FR通过GPI锚固定在膜上,并在上皮和非上皮起源的恶性组织中表达。 γ-FR在造血起源的组织中表达,例如脾,胸腺和骨髓。 delta-FR的表达模式难以捉摸,这表明它在空间和时间上都受到高度限制。叶酸受体的α同工型被用作高度选择性的肿瘤标志物,并且可以通过与叶酸衍生物偶联而靶向将治疗性化合物递送至肿瘤细胞。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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