Human GSTM1 ELISA Kit ELISA试剂盒,Human GSTM1 ELISA Kit/人GSTM1 ELISA试剂盒

2024-10-23

Human GSTM1 ELISA Kit/人GSTM1 ELISA试剂盒

货号:EH233RB,EH233RBX5,EH233RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,28472,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

2 ng/mL

检测范围2-500 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameGSTM1
Protein aliasesglutathione S-alkyltransferase, glutathione S-aralkyltransferase, glutathione S-aryltransferase, glutathione S-transferase M1, Glutathione S-transferase Mu 1, GST class-mu 1, GST HB subunit 4, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, HB subunit 4, S-(hydroxyalkyl)glutathione lyase

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesGST1, GSTM1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1
Gene ID(Human) 2944
Gene symbolGSTM1
UniProt ID(Human) P09488
Human GSTM1 quantitates human GSTM1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human GSTM1.人GSTM1对血清,血浆,上清液中的人GSTM1进行定量。 该检测试剂盒将专门识别天然和重组人GSTM1。Target information 靶标信息Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13. 3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.谷胱甘肽S-转移酶的胞质和膜结合形式由两个不同的超基因家族编码。目前,已经鉴定出八种不同的可溶性细胞质哺乳动物谷胱甘肽S-转移酶:α,κ,μ,ω,pi,σ,θ和ζ。该基因编码属于mu类的谷胱甘肽S-转移酶。 mu类酶通过与谷胱甘肽结合,对包括致癌物,治疗药物,环境毒素和氧化应激产物的亲电子化合物进行解毒。编码mu类酶的基因组织在1p13号染色体上的基因簇中。 3,并且是高度多态的。这些遗传变异可以改变个体对致癌物和毒素的敏感性,并影响某些药物的毒性和功效。此类mu基因的空突变与多种癌症的增加有关,这可能是由于对环境毒素和致癌物的敏感性增加所致。该基因的转录变体编码多种蛋白质同工型。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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