PKC gamma Monoclonal Antibody (PKC66)

货号：13-3800

规格：200 µg

价格：4809

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Purified rat brain PKC.

物种：人/小鼠/大鼠

宿主：小鼠

抗体亚型：IgG1, kappa

克隆号：PKC66

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.5 mg/mL	用法：	2-5 µg/mL(WB)

靶标信息Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC gamma is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

数据：

PKC gamma Antibody (13-3800)The Journal of comparative neurology 2014 -Published figure using PKC gamma monoclonal antibody (Product # 13-3800)

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技术参数

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