Human Matrilin-3 ELISA Kit ELISA试剂盒,Human Matrilin-3 ELISA Kit/人Matrilin-3 ELISA试剂盒

2024-10-24

Human Matrilin-3 ELISA Kit/人Matrilin-3 ELISA试剂盒

货号:EH314RB,EH314RBX5,EH314RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

20 pg/mL

检测范围20-5,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameMatrilin 3
Protein aliasesMatrilin-3

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesDIPOA, EDM5, HOA, MATN3, OADIP, OS2
Gene ID(Human) 4148
Gene symbolMATN3
UniProt ID(Human) O15232
Human Matrilin-3 quantitates human Matrilin-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Matrilin-3.人Matrilin-3定量分析血清,血浆,上清液中的人Matrilin-3。 该检测试剂盒将只识别天然和重组人Matrilin-3。Target information 靶标信息Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.Matrilins(MATNs)是非胶原细胞外基质(ECM)蛋白家族,由四个已知成员组成,这些成员已被提议在间充质干细胞(MSCs)软骨形成过程中调节细胞表型中发挥关键作用。 MATN1和MATN3在软骨中特异性表达,并且在软骨形成过程中是上调最严重的ECM蛋白之一。 MATN3由单个N端von Willebrand因子A(vWFA)域组成,后接四个表皮生长因子(EGF)重复序列和卷曲螺旋域,而MATN1由两个被一个EGF样域隔开的vWFA域组成。 MATN1或MATN3可能在软骨细胞分化过程中调节软骨形成中发挥作用。该基因的突变与多种遗传性软骨发育不良有关。最近的研究表明,MATN3的异常表达和加工是常规软骨肿瘤的标志。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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