MLL1 Recombinant Rabbit Monoclonal Antibody (BL-175-7E8)

货号：A700-010

规格：100μL

价格：4158

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Between 720 and 780

物种：人

宿主：兔

抗体亚型：IgG

克隆号：BL-175-7E8

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	10 µl/0.5 mg lysate (IP);1:1,000(WB)

产品详细信息The recommended shelf life for this product is 1 year from date of receipt. 靶标信息KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis. It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation. KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity. It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.

数据：

MLL1 Antibody (A700-010) in WB Detection of human MLL1 by WB of immunoprecipitates from 293T lysate. Antibodies: Rabbit anti-MLL1 recombinant monoclonal [BL-175-7E8] (A700-010) and rabbit anti-MLL1 antibodies (A300-086A, A300-087A). Secondary: ReliaBLOT® reagents (WB120). MLL1 Antibody (A700-010) in WBDetection of human MLL1 by WB in 293T, HeLa, MCF1, HepG2, A459, and SW620 lysate. Antibody: Rabbit anti-MLL1 recombinant monoclonal [BL-175-7E8] (A700-010). Secondary: HRP-conjugated goat anti-rabbit IgG (A120-101P).

推荐产品：

二抗荧光二抗免疫组化一抗标签抗体

技术参数

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-46824.htm