Human Caspase-1 ELISA Kit ELISA试剂盒,Human Caspase-1 ELISA Kit/人Caspase-1 ELISA试剂盒

2024-10-24

Human Caspase-1 ELISA Kit/人Caspase-1 ELISA试剂盒

货号:EH70RB,EH70RBX5,EH70RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.43 ng/mL

检测范围0.43-100 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCaspase 1
Protein aliasesCASP-1, CASP1 nirs variant 1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), Caspase-1, Caspase-1 subunit p10, Caspase-1 subunit p20, ICE, IL-1 beta-converting enzyme, IL-1BC, IL1B-convertase, interleukin 1, convertase, interleukin 1-B converting enzyme, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCASP1, ICE, IL1BC, IL1BCE, P45
Gene ID(Human) 834
Gene symbolCASP1
UniProt ID(Human) P29466
Human Caspase-1 quantitates human Caspase-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Caspase-1.人Caspase-1定量测定血清,血浆,上清液中的人Caspase-1。 该检测试剂盒将专门识别天然和重组人Caspase-1。Target information 靶标信息Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.胱天蛋白酶是半胱氨酸蛋白酶的家族,其可以分为凋亡和炎性胱天蛋白酶亚家族。 与凋亡的胱天蛋白酶不同,炎性亚家族的成员通常不参与细胞死亡,但与对微生物病原体的免疫反应有关。 该亚家族的成员包括caspase-1,-4,-5和-12,可以激活促炎细胞因子,例如IL-1-b和IL-18。 最初将Caspase-1鉴定为IL-1b转换酶。 后来的实验表明,它是秀丽隐杆线虫细胞死亡基因ced-3的哺乳动物同源物,其过度表达可诱导成纤维细胞凋亡。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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