Human Caspase-7 ELISA Kit ELISA试剂盒,Human Caspase-7 ELISA Kit/人Caspase-7 ELISA试剂盒

2024-10-24

Human Caspase-7 ELISA Kit/人Caspase-7 ELISA试剂盒

货号:EH71RB,EH71RBX5,EH71RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.62 ng/mL

检测范围0.62-150 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCaspase 7
Protein aliasesApoptotic protease Mch-3, CASP-7, caspase 7, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, Caspase-7, Caspase-7 subunit p11, Caspase-7 subunit p20, CMH-1, ICE-LAP3, ICE-like apoptotic protease 3

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCASP-7, CASP7, CMH-1, ICE-LAP3, LICE2, MCH3
Gene ID(Human) 840
Gene symbolCASP7
UniProt ID(Human) P55210
Human Caspase-7 quantitates human Caspase-7 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Caspase-7.人Caspase-7定量测定血清,血浆,上清液中的人Caspase-7。 该检测试剂盒将专门识别天然和重组人Caspase-7。Target information 靶标信息Caspase 7 is part of a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase 7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression. Alternative splicing results in four transcript variants, encoding three distinct isoforms of Caspase 7. Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.Caspase 7是半胱氨酸蛋白酶家族的一部分,可分为凋亡和炎性的Caspase亚家族。与凋亡的胱天蛋白酶不同,炎性亚家族的成员通常不参与细胞死亡,但与对微生物病原体的免疫反应有关。凋亡亚家族可以进一步分为响应死亡信号而被激活的启动子胱天蛋白酶和被启动子胱天蛋白酶激活并负责最终导致细胞死亡的细胞底物的裂解的execution子手胱天蛋白酶。半胱天冬酶7是一种c子手半胱天冬酶,其基于与半胱天冬酶1和3,秀丽隐杆线虫细胞死亡蛋白CED-3的同源性而鉴定。 Caspase-7 mRNA的可变剪接导致产生3种不同的亚型。 Caspase-7活性可以被XIAP表达直接抑制。选择性剪接导致编码四个半胱天冬酶7的三个不同亚型的四个转录物变体。与CASP7相关的疾病包括1型糖尿病17和阿留申水貂病。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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