Human CD36/SR-B3 ELISA Kit ELISA试剂盒,Human CD36/SR-B3 ELISA Kit/人CD36 / SR-B3 ELISA试剂盒

2024-10-24

Human CD36/SR-B3 ELISA Kit/人CD36 / SR-B3 ELISA试剂盒

货号:EH88RB,EH88RBX5,EH88RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

2 ng/mL

检测范围2-500 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD36
Protein aliasesCD36, CD36 antigen (collagen type I receptor, thrombospondin receptor), CD36 molecule (thrombospondin receptor), cluster determinant 36, FAT, Fatty acid translocase, Glycoprotein IIIb, GPIIIB, GPIV, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, PAS-4 protein, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, scavenger receptor class B, member 3, Thrombospondin receptor

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesBDPLT10, CD36, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3
Gene ID(Human) 948
Gene symbolCD36
UniProt ID(Human) P16671
Human CD36/SR-B3 quantitates human CD36/SR-B3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD36/SR-B3.人CD36 / SR-B3定量检测血清,血浆,上清液中的人CD36 / SR-B3。该检测试剂盒将专门识别天然和重组人CD36 / SR-B3。Target information 靶标信息CD36 (fatty acid translocase, FAT) is an 88 kDa, ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similar to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. Further, CD36 may function as a cell adhesion molecule and directly mediates cyto-adherence of Plasmodium falciparum parasitized erythrocytes. Mutations in the CD36 gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the CD36 protein have been found.CD36(脂肪酸转位酶,FAT)是一种88 kDa的双位糖基化蛋白,属于清除剂受体的B类家族。 CD36由大多数静止的边缘区B细胞表达,但不由滤泡和B1 B细胞表达,并且在TLR和CD40刺激下,在体外在滤泡B细胞上迅速诱导CD36。 CD36不影响B细胞的发育,但可以调节一抗和二抗。与葡萄糖转运蛋白GLUT4相似,在胰岛素刺激细胞后,CD36从细胞内池转移到质膜。在小鼠中,CD36负责味觉长链脂肪酸。 CD36优先在脂质筏中发现,这有助于其与受体,信号传导和衔接子分子缔合。 CD36与胶原蛋白,血小板反应蛋白,阴离子磷脂和氧化的LDL结合。此外,CD36可以充当细胞粘附分子,并直接介导恶性疟原虫寄生的红细胞的细胞粘附。 CD36基因的突变会导致血小板糖蛋白缺乏。已经发现了编码CD36蛋白的多个选择性剪接的转录变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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