组蛋白甲基化修饰,H3K9,多克隆抗体,EHMT1 Polyclonal Antibody

2024-10-24

EHMT1 Polyclonal Antibody

货号:PA5-111499

规格:100 µL

价格:6301

产品类型:标签抗体

品牌:Thermo Fisher

抗原:Recombinant Protein corresonding to Human EHMT1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:其它

类型:一抗同型对照:
浓度: 用法: 0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF)
产品详细信息Immunogen sequence: ADGETNGSCE NSDASSHANA AKHTQDSARV NPQDGTNTLT RIAENGVSER DSEAAKQNHV TADDFVQTSV IGSNGYILNK PALQAQPLRT TSTLASSLPG HAAKTLPGGA GKGRTPSAFP QTPAAPPATL 靶标信息EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
数据:

EHMT1 Antibody (PA5-111499) in ICCImmunofluorescent staining of EHMT1 in human cell line MCF7 using EHMT1 Polyclonal Antibody (Product # PA5-111499) shows localization to nucleoplasm and nuclear bodies.
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