Human Alpha 2-M ELISA Kit ELISA试剂盒,Human Alpha 2-M ELISA Kit/人Alpha 2-M ELISA试剂盒

2024-10-24

Human Alpha 2-M ELISA Kit/人Alpha 2-M ELISA试剂盒

货号:EH20RB,EH20RBX5,EH20RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

4 ng/mL

检测范围4-3,000 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameA2M
Protein aliasesAlpha-2-M, Alpha-2-macroglobulin, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesA2M, A2MD, CPAMD5, FWP007, S863-7
Gene ID(Human) 2
Gene symbolA2M
UniProt ID(Human) P01023
Human Alpha 2-M quantitates human Alpha 2-M in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Alpha 2-M.人Alpha 2-M定量检测血清,血浆,上清液中的Alpha 2-M。 该检测试剂盒将专门识别天然和重组人Alpha 2-M。Target information 靶标信息Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.α2-巨球蛋白(a2M)是大约720 kDa的同四聚体糖蛋白,由四个相同的大约180 kDa的亚基组成。 aAlpha 2M与其他α-巨球蛋白(例如补体成分C3和C4和妊娠区蛋白PZP)共享,对多种配体具有非凡的结合能力。 这允许α-巨球蛋白充当针对血浆中外源肽的体液防御屏障。 Alpha 2M相互作用并捕获几乎任何蛋白酶,通常称为泛蛋白酶抑制剂。 在阿尔茨海默氏病(AD)患者的大脑中,Alpha 2M也已经被定位为弥散性淀粉样斑块,支持了alpha 2M在AD病因学中的重要作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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