Human Cathepsin C ELISA Kit ELISA试剂盒,Human Cathepsin C ELISA Kit/人组织蛋白酶C ELISA试剂盒

2024-10-24

Human Cathepsin C ELISA Kit/人组织蛋白酶C ELISA试剂盒

货号:EH73RB,EH73RBX5,EH73RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

2 ng/mL

检测范围2-500 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCathepsin C
Protein aliasesCathepsin C, Cathepsin J, Dipeptidyl peptidase 1, Dipeptidyl peptidase 1 exclusion domain chain, Dipeptidyl peptidase 1 heavy chain, Dipeptidyl peptidase 1 light chain, Dipeptidyl peptidase I, Dipeptidyl peptidase I exclusion domain chain, Dipeptidyl peptidase I heavy chain, Dipeptidyl peptidase I light chain, Dipeptidyl transferase, dipeptidyl-peptidase I, DPP-I

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCPPI, CTSC, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS
Gene ID(Human) 1075
Gene symbolCTSC
UniProt ID(Human) P53634
Human Cathepsin C quantitates human Cathepsin C in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cathepsin C.人组织蛋白酶C可定量测定血清,血浆,上清液中的人组织蛋白酶C。该检测试剂盒将专门识别天然和重组人组织蛋白酶C。Target information 靶标信息Cathepsin C, known also as dipeptidyl aminopeptidase I (DPPI), is a tetrameric lysosomal cysteine peptidase belonging to the papain family. Cathepsin C is involved in intracellular protein degradation and the processing of protein precursors, where it participates in cell growth, neuraminidase activation, and platelet factor XIII activation. Cathepsin C is largely related to other lysosomal cysteine proteinases, including cathepsin B, H and L. Enzymatically, Cathepsin C is capable of sequentially removing dipeptides from the amino terminus, and it requires halide ions, namely chloride ions, and thiols for complete enzymatic activity. Protein levels of Cathepsin C are detected in a variety of tissues, and it is most highly expressed in spleen, kidney, cytotoxic lymphocytes and myeloid cells, where it localizes to the secretory granule compartment. Cathepsin C is initially synthesized as a proenzyme that is rapidly processed to generate two distinct chains that function together as the mature form of the enzyme.组织蛋白酶C,也称为二肽基氨基肽酶I(DPPI),是属于木瓜蛋白酶家族的四聚体溶酶体半胱氨酸肽酶。组织蛋白酶C参与细胞内蛋白质降解和蛋白质前体的加工,在其中参与细胞生长,神经氨酸酶活化和血小板因子XIII活化。组织蛋白酶C在很大程度上与其他溶酶体半胱氨酸蛋白酶有关,包括组织蛋白酶B,H和L。在酶学上,组织蛋白酶C能够从氨基末端顺序去除二肽,并且它需要卤离子(即氯离子)和硫醇才能完全发挥酶的作用。 。在多种组织中都检测到组织蛋白酶C的蛋白质水平,并且在脾脏,肾脏,细胞毒性淋巴细胞和髓样细胞中高度表达,并定位在分泌性颗粒腔室中。组织蛋白酶C最初是作为一种原酶进行合成的,可以快速加工以生成两条不同的链,这些链一起作为酶的成熟形式发挥作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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