Human EN-RAGE/S100A12 ELISA Kit ELISA试剂盒,Human EN-RAGE/S100A12 ELISA Kit/人EN-RAGE / S100A12 ELISA试剂盒

2024-10-24

Human EN-RAGE/S100A12 ELISA Kit/人EN-RAGE / S100A12 ELISA试剂盒

货号:EH170RB,EH170RBX5,EH170RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.82 ng/mL

检测范围0.82-200 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameS100A12
Protein aliasesCAAF1, CAGC, Calcitermin, Calcium-binding protein in amniotic fluid 1, calgranulin C, Calgranulin-C, CGRP, EN-RAGE, Extracellular newly identified RAGE-binding protein, Migration inhibitory factor-related protein 6, MRP-6, Neutrophil S100 protein, Protein S100-A12, S100 calcium-binding protein A12, S100 calcium-binding protein A12 (calgranulin C)

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6, S100A12
Gene ID(Human) 6283
Gene symbolS100A12
UniProt ID(Human) P80511
Human EN-RAGE/S100A12 quantitates human EN-RAGE/S100A12 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human EN-RAGE/S100A12.人EN-RAGE / S100A12定量测定血清,血浆,上清液中的人EN-RAGE / S100A12。 该检测试剂盒将专门识别天然和重组人EN-RAGE / S100A12。Target information 靶标信息S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.S100A12是包含2个EF手钙结合基序的S100蛋白家族的成员。 S100蛋白位于大量细胞的细胞质和/或细胞核中,并参与许多细胞过程的调控,例如细胞周期进程和分化。 S100A12被提议参与特定的钙依赖性信号转导途径,其对细胞骨架成分的调节作用可能会调节各种中性粒细胞的活性。 S100A12还是RAGE的配体。 与RAGE在单核吞噬细胞,淋巴细胞和内皮细胞上的相互作用触发细胞活化。 S100A12 / RAGE可激活核因子κB(炎症事件的关键转录因子)。 S100A12也已被证明具有抗微生物特性。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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