Human CNTF R alpha ELISA Kit ELISA试剂盒,Human CNTF R alpha ELISA Kit/人CNTF R alpha ELISA试剂盒

2024-10-24

Human CNTF R alpha ELISA Kit/人CNTF R alpha ELISA试剂盒

货号:EH114RB,EH114RBX5,EH114RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

12 pg/mL

检测范围12-3,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCNTFR
Protein aliasesCiliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCNTFR
Gene ID(Human) 1271
Gene symbolCNTFR
UniProt ID(Human) P26992
Human CNTF R alpha quantitates human CNTF R alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CNTF R alpha.人CNTF R alpha定量检测血清,血浆,上清液中的人CNTF R alpha。该检测试剂盒将只识别天然和重组人CNTF Rα。Target information 靶标信息This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.该基因编码属于受体细胞因子超家族的造血素/干扰素类受体。编码的基因产物代表形成CNTF受体复合物的异三聚体的CNTF特异性α亚基,该复合物还包括LIFR和gp130。该受体通过糖基磷脂酰肌醇键连接至膜,并包含免疫球蛋白样C2型结构域和纤连蛋白III型结构域。信号转导要求CNTF首先结合该alpha成分,从而允许募集gp130和LIFR beta形成三重受体复合物。信号转导刺激多种神经元细胞类型的基因表达,细胞存活或分化。在该基因座处已观察到替代剪接,并且已鉴定出两个均编码相同蛋白质的变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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