Human SCF R/CD117/c-kit ELISA Kit ELISA试剂盒,Human SCF R/CD117/c-kit ELISA Kit/人SCF R / CD117 / c-kit ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human SCF R/CD117/c-kit ELISA Kit ELISA试剂盒,Human SCF R/CD117/c-kit ELISA Kit/人SCF R / CD117 / c-kit ELISA试剂盒

2024-10-24

Human SCF R/CD117/c-kit ELISA Kit/人SCF R / CD117 / c-kit ELISA试剂盒

货号：EH403RB,EH403RBX5,EH403RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	45 pg/mL
检测范围	45-10,000 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	c-Kit (CD117)
Protein aliases	CD117, Mast/stem cell growth factor receptor Kit, p145 c-kit, PBT, Piebald trait protein, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFR, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	C-Kit, CD117, KIT, PBT, SCFR
Gene ID	(Human) 3815
Gene symbol	KIT
UniProt ID	(Human) P10721

Human SCF R/CD117/c-kit quantitates human SCF R/CD117/c-kit in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SCF R/CD117/c-kit.人SCF R / CD117 / c-kit定量分析血清，血浆，上清液中的人SCF R / CD117 / c-kit。该检测试剂盒将专门识别天然和重组人SCF R / CD117 / c-kit。Target information 靶标信息c-Kit, also known as mast/stem cell growth factor receptor (SCFR) or CD117, is a trans membrane type III tyrosine kinase receptor encoded by the c-Kit proto-oncogene, located on chromosome 4 in humans. It is expressed in hematopoietic stem cells, germ cells, mast cells and gastrointestinal tract cajal cells. Upon binding of its ligand stem cell factor (SCF), c-kit dimerizes, resulting in receptor activation and autophosphorylation of various tyrosine residues including tyrosine 703 located on the cytoplasmic domain of the receptor. This modification allows docking of Grb2 and activation of the Ras/ERK signaling pathway. SCF/c-kit can activate multiple downstream signaling pathways including PI3K, PLC-gamma and JAK/STAT. c-kit receptor activation is essential for hematopoiesis, stem cell maintenance and gametogenesis.c-Kit，也称为肥大/干细胞生长因子受体（SCFR）或CD117，是由c-Kit原癌基因编码的跨膜III型酪氨酸激酶受体，位于人类的第4号染色体上。它在造血干细胞，生殖细胞，肥大细胞和胃肠道唾液细胞中表达。结合其配体干细胞因子（SCF）后，c-kit发生二聚化，导致受体活化和各种酪氨酸残基（包括位于受体胞质域上的酪氨酸703）的自磷酸化。这种修饰可以使Grb2停靠并激活Ras / ERK信号通路。 SCF / c-kit可以激活多个下游信号传导途径，包括PI3K，PLC-γ和JAK / STAT。 c-kit受体激活对于造血，干细胞维持和配子发生至关重要。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

技术参数

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Human SCF R/CD117/c-kit ELISA Kit ELISA试剂盒,Human SCF R/CD117/c-kit ELISA Kit/人SCF R / CD117 / c-kit ELISA试剂盒

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