Rat IL-23 ELISA Kit ELISA试剂盒,Rat IL-23 ELISA Kit/大鼠IL-23 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat IL-23 ELISA Kit ELISA试剂盒,Rat IL-23 ELISA Kit/大鼠IL-23 ELISA试剂盒

2024-10-24

Rat IL-23 ELISA Kit/大鼠IL-23 ELISA试剂盒

货号：ERA28RB,ERA28RBX5

规格：96 Tests,5X96 Tests

价格：6327,28472

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：大鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.82 ng/mL
检测范围	0.82-200 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	IL-23 p19
Protein aliases	IL-23 subunit alpha, IL-23-A, IL-23p19, Interleukin-23 subunit alpha, Interleukin-23 subunit p19
物种（Tested）	大鼠
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	Il23a
Gene ID	(Rat) 155140
Gene symbol	Il23a
UniProt ID	(Rat) Q91Z84

Rat IL-23 quantitates rat IL-23 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat IL-23.大鼠IL-23定量测定血清，血浆，上清液中的大鼠IL-23。该检测试剂盒将只识别天然和重组大鼠IL-23。Target information 靶标信息IL-23 is a heterodimeric cytokine composed of the p40 subunit of IL-12 disulfide-linked with a protein p19. p19, like p35 of IL-12, is biologically inactive by itself. IL-23 interacts with IL-12Rbeta1 and an additional, novel beta2-like receptor subunit with STAT4 binding domain, termed IL-23R. IL-23 is secreted by activated mouse and human dendritic cells. Biological activities of mouse IL-23 are distinct from those of mouse IL-12. Mouse IL-23 was found not to induce significant amounts of IFN-γ. Mouse IL-23 does induce strong proliferation of memory T cells (but not naive T cells), whereas IL-12 has no effect on memory cells. Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the proinflammatory cytokine IL-17. Human IL-23 has biological properties which are less distinct from human IL-12; human IL-23 induces proliferation of memory T cells and induces moderate levels of IFN-γ production by naive and memory T cells, as compared to IL-12.IL-23是一种异源二聚体细胞因子，由与蛋白质p19连接的IL-12二硫键的p40亚基组成。与IL-12的p35一样，p19本身也没有生物学活性。 IL-23与IL-12Rbeta1和另一个具有STAT4结合域的新型beta2样受体亚基（称为IL-23R）相互作用。 IL-23由活化的小鼠和人树突状细胞分泌。小鼠IL-23的生物学活性不同于小鼠IL-12的生物学活性。发现小鼠IL-23不会诱导大量的IFN-γ。小鼠IL-23确实会诱导记忆T细胞（而非幼稚T细胞）强烈增殖，而IL-12对记忆细胞没有影响。此外，小鼠IL-23（但不是IL-12）可以激活小鼠记忆T细胞以产生促炎性细胞因子IL-17。人IL-23具有与人IL-12不同的生物学特性；与IL-12相比，人IL-23诱导记忆T细胞增殖并诱导幼稚和记忆T细胞中等水平的IFN-γ产生。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Rat IL-23 ELISA Kit ELISA试剂盒,Rat IL-23 ELISA Kit/大鼠IL-23 ELISA试剂盒

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