Rat VEGFR1 ELISA Kit ELISA 试剂盒,Rat VEGFR1 ELISA Kit/大鼠VEGFR1 ELISA 试剂盒

2024-10-24

Rat VEGFR1 ELISA Kit/大鼠VEGFR1 ELISA 试剂盒

货号:ERA59RB,ERA59RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:大鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.41 ng/mL

检测范围0.41-100 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameVEGF Receptor 1
Protein aliasesFLT-1, FMS-like tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1

物种(Tested)

大鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesVEGFR-1
Gene ID(Rat) 54251
Gene symbolFlt1
Rat VEGFR1 quantitates rat VEGFR1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat VEGFR1.大鼠VEGFR1定量测定血清,血浆,上清液中的大鼠VEGFR1。该检测试剂盒将只识别天然和重组大鼠VEGFR1。Target information 靶标信息Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.酪氨酸蛋白激酶,可作为VEGFA,VEGFB和PGF的细胞表面受体,在胚胎脉管系统的发育,血管新生,细胞存活,细胞迁移,巨噬细胞功能,趋化性和癌细胞的调节中起重要作用入侵。通过抑制内皮细胞的过度增殖,可能作为胚胎血管生成的负调节剂发挥重要作用。可以促进成年后内皮细胞的增殖,存活和血管生成。它促进细胞增殖的功能似乎是细胞类型特异性的。促进PGF介导的内皮细胞增殖,某些类型癌细胞的增殖,但不促进正常成纤维细胞(体外)的增殖。对VEGFA有很高的亲和力,蛋白激酶活性相对较低;通过限制游离VEGFA的量并防止其与KDR结合,其可以作为VEGFA信号转导的负调节剂。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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