Rat Agrin ELISA Kit ELISA试剂盒,Rat Agrin ELISA Kit/大鼠Agrin ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat Agrin ELISA Kit ELISA试剂盒,Rat Agrin ELISA Kit/大鼠Agrin ELISA试剂盒

2024-10-24

Rat Agrin ELISA Kit/大鼠Agrin ELISA试剂盒

货号：ERA2RB,ERA2RBX5

规格：96 Tests,5X96 Tests

价格：6641,29884

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：大鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.06 ng/mL
检测范围	0.06-50 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	Agrin
Protein aliases	Agrin, Agrin C-terminal 110 kDa subunit, Agrin C-terminal 22 kDa fragment, Agrin C-terminal 90 kDa fragment, Agrin N-terminal 110 kDa subunit, C22, C90
物种（Tested）	大鼠
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	AGR, Agrin, Agrn
Gene ID	(Rat) 25592
Gene symbol	Agrn
UniProt ID	(Rat) P25304

Rat Agrin quantitates rat Agrin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat Agrin.大鼠凝集素定量测定血清，血浆，上清液中的大鼠凝集素。该测定法将专门识别天然和重组大鼠凝集素。Target information 靶标信息Agrin is a molecule that resides in the basal lamina of muscle cells and directs key events in post synaptic differentiation. Most notably, Agrin is responsible for the clustering of acetylcholine receptors (AChRs) on the cell surface and their localization to the neuromuscular junction. Several Agrin variants have been identified which arise from alternative mRNA splicings. Agrin splice forms having inserts at two sites in the carboxy terminus designated "y" and "z" display a high affinity for AChRs, while splice forms lacking these inserts associate with AChRs weakly. Muscle alpha-dystroglycan has been postulated to be the receptor for the clustering activity of agrin; however, this is a point of contention. Tyrosine phosphorylation has been implicated as a required early step in AChR aggregation. Interestingly, a unique receptor tyrosine kinase, designated MuSK, has been discovered that interacts with Agrin and is specifically localized to developing muscle.Agrin是一种驻留在肌肉细胞基底层中的分子，指导突触后分化中的关键事件。最值得注意的是，Agrin负责乙酰胆碱受体（AChR）在细胞表面的聚集以及它们在神经肌肉接头中的定位。已经发现了几种Agrin变体，它们是由其他mRNA剪接产生的。 Agrin剪接形式在羧基末端的两个位点分别标记为“ y”和“ z”，显示出对AChR的高度亲和力，而缺少这些插入的剪接形式与AChRs弱相关。假定肌肉α-营养不良聚糖是凝集素聚集活性的受体。但是，这是一个争论点。酪氨酸磷酸化已被认为是AChR聚集所需的早期步骤。有趣的是，已经发现了一种独特的受体酪氨酸激酶，称为MuSK，它与Agrin相互作用并且特异性地定位于发育中的肌肉。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Rat Agrin ELISA Kit ELISA试剂盒,Rat Agrin ELISA Kit/大鼠Agrin ELISA试剂盒

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