Rat E-Selectin ELISA Kit ELISA试剂盒,Rat E-Selectin ELISA Kit/大鼠E-选择素ELISA试剂盒

2024-10-24

Rat E-Selectin ELISA Kit/大鼠E-选择素ELISA试剂盒

货号:ERA14RB,ERA14RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:大鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.13 ng/mL

检测范围0.13-20 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameE-selectin (CD62E)
Protein aliasesCD62 antigen-like family member E, CD62E, E-selectin, ELAM-1, Endothelial leukocyte adhesion molecule 1, LECAM2, Leukocyte-endothelial cell adhesion molecule 2, selectin, endothelial cell

物种(Tested)

大鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesElam-1, Sele
Gene ID(Rat) 25544
UniProt ID(Rat) P98105
Gene symbolSele
Rat E-Selectin quantitates rat E-Selectin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat E-Selectin.大鼠E-选择素定量测定血清,血浆,上清液中的大鼠E-选择素。该检测试剂盒将专门识别天然和重组大鼠E-选择素。Target information 靶标信息Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.白细胞在毛细血管后小静脉的淋巴结外渗时粘附在血管内皮上。另外,炎症发作后,白细胞粘附发生在体内任何部位的毛细血管和小静脉中。这种反应是即时的,涉及一系列的粘附受体。在选择蛋白和免疫球蛋白超家族的内皮表面成员参与该级联反应。选择素是C型细胞表面凝集素,在白细胞粘附于血管壁内皮细胞中发挥作用。 E-选择素(CD62E)是一种内皮细胞特异性选择素,仅在被促炎性细胞因子激活后才会表达。体外实验表明,IL-1,TNFα和细菌壁成分(如脂多糖)在依赖NFkB的信号级联反应中诱导E-选择蛋白的转录。 E-选择蛋白已在多种炎症情况下与血管内皮相关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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