Rat IL-6 ELISA (For Lysates) Kit ,Rat IL-6 ELISA (For Lysates) Kit/大鼠IL-6 ELISA(用于裂解液)试剂盒

2024-10-24

Rat IL-6 ELISA (For Lysates) Kit/大鼠IL-6 ELISA(用于裂解液)试剂盒

货号:ERA32RB,ERA32RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:大鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

15 pg/mL

检测范围30-10,000 pg/mL

样本类型/体积

细胞裂解液 50 μL

组织匀浆 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameIL-6
Protein aliasesIL-6, Interleukin 6 (interferon, beta 2), Interleukin-6

物种(Tested)

大鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesIfnb2, Il-6, Il6, ILg6
Gene ID(Rat) 24498
Gene symbolIl6
UniProt ID(Rat) P20607
Rat IL-6 quantitates rat IL-6 in cell lysate, tissue homogenate. The assay will exclusively recognize both natural and recombinant rat IL-6.大鼠IL-6定量测定细胞裂解液,组织匀浆中的大鼠IL-6。该检测试剂盒将只识别天然和重组大鼠IL-6。Target information 靶标信息Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.白介素6(IL-6)是一种多功能的26 kD蛋白,最初是在RNA刺激的成纤维细胞样细胞的培养基中发现的。 IL-6似乎直接参与感染和细胞损伤后发生的反应,它可能被证明在调节急性期反应中作为IL-1和TNF-a很重要。据报道IL-6由成纤维细胞,活化的T细胞,活化的单核细胞或巨噬细胞和内皮细胞产生。 IL-6作用于多种细胞,包括骨髓祖细胞,T细胞,B细胞和肝细胞。另外,IL-6似乎在T淋巴细胞的增殖中与IL-2相互作用。 IL-6增强了IL-3对多能造血祖细胞的增殖作用。 IL-6在B细胞向浆细胞的分化中起关键作用,并且是浆细胞瘤和骨髓瘤的有效生长因子。 IL-6是一种非常有用的培养补充剂,可用于产生大量产生抗体的杂交瘤。 IL-6主要在急性和慢性炎症部位产生,分泌到血清中并通过白介素6受体α诱导转录炎症反应。 IL-6的功能涉及多种与炎症相关的疾病状态,包括糖尿病和全身性青少年类风湿性关节炎。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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